Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC331H506N84O78S10

DescriptionStandard

        MKIHGFLFVLFFFLVPIATRVKCAMKDTYSCFIMRGKCRHECHDFEKPIGFCTKLNVNCYM
    

Molecular Weight7230.72 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)4.70

Net Charge (pH 7.4) 4.23

Charge Density (pH 7.0) 0.0771

GRAVY Index0.35

Hydrophobic Moment 0.50

Boman Index0.14

Instability Index34.23

Aliphatic Index 73.44

Aromaticity 0.1639

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2576.36

LogP -14.12

H-bond Donors 96.0

H-bond Acceptors 96.0

Rotatable Bonds 237.0

Heavy Atoms 503.0

Ring Count 15.0

Amide Bonds 62.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0206225 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyDefensin

Tax ID9595

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence