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MYP_032434
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Basic Information
GBVA10-13(C1K/Y8K/T15K/T18K)
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
18 amino acids
C110H192N36O19
Standard
Sequence
KWVRLGRKLLRRLKKPFK
Physicochemical Analysis
2322.93 Da
12.00
8.76
8.54
0.4864
-1.01
1.02
-0.54
35.98
102.78
0.1111
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
942.72
-3.72
36.0
28.0
83.0
165.0
4.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0140775 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HCV Entry inhibition
Hepatitis C virus(Jc1-Luc HCVcc) | Huh7.5.1 cells
20 μM
IC50
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. | Liu X, Huang Y, Cheng M, Pan L, Si Y, Li G, Niu Y, Zhao L, Zhao J, Li X, Chen Y, Yang W. | J Virol. 2013 Feb;87(3):1649-57. | DOI:10.1128/JVI.02201-12 | PMID:23175359 PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0221231 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
hepatitis C virus(Jc1-Luc HCVcc):inhibition of virus entry in Huh7
PaperPubMed PMID: 23175361 PMID23175361 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175361/
RECORD: Rec_0319989 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Hepatitis C virus (HCV) PsV
PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
RECORD: Rec_0335338 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
5
PaperPubMed PMID: 23175361 PMID23175361 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175361/
RECORD: Rec_0365513 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
cells
20 μM
IC50
PaperPubMed PMID: 23175361 PMID23175361 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175361/
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