MYP_032423
Unnamed
Venom / Toxin
▸
General toxin
▸
Toxin
Venom / Toxin
▸
Toxin
Standard
25 amino acids
C98H169N35O34S6
Standard
CKGTGKSCSRIAYNCCTGSCRSGKC
2573.99 Da
9.15
4.70
4.40
0.1879
-0.42
0.55
-0.21
52.47
19.60
0.0400
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1148.28
-20.33
49.0
45.0
87.0
173.0
1.0
25.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0028694
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Miscellaneous
RECORD: Rec_0122952
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
1-16; 8-20; 15-25
Bio-Activity Profile
Toxin
Venom
RECORD: Rec_0244013
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 44.0%, C 56.0% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Miscellaneous
RECORD: Rec_0433366
VERIFIED: YES
Provenance & Taxonomy
Conus fulmen [Animal]
ω-conotoxin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Three disulfide bonds reported (1st-4th, 2nd-5th, 3rd-6th cysteines)
Bio-Activity Profile
N-type calcium channel inhibitor
Calcium channel blocker
Analgesic
Toxin
Venom
human N-type voltage-gated Ca2+ channel (CaV2.2); C2D7 (HEK293-derived) cells
11.5±1.4 nM
IC50 (whole-cell N-type Ca2+ current inhibition)