Peptide Database

Peptide NameKiller protein of pyocin s3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length557 amino acids

Chemical FormulaC2720H4264N756O814S23

DescriptionStandard

        MAIGYFLLVGDKTTCGGQIITGDHTMTFDGRATAREGDKVTCGKHSGTYMIVGGISDMFDMGQRLAGTLDSVSTCPCKARFINSIMDCYEKESQPVNQAVAPANMAAQNLSSPVGKTVGVQSGPPPVPKAPPPIPVFTKSCLRGKGCTDAGTEAEPANNFGRMAVYQVPSSPAPVTLQKPEPPPQGKQHPPEPDKPQDKKLPWYKRWFSRGKDKAEAAATAVAATARSAVEEGEGLVMRYIGGGATSAGRWLAAPNPVTVGLMGLFYSPELNQGEEDYLNQYQLRQIAEQFGKAPTRVRFRWIRDEKSGRMTIQGYHVSPESGLDKVPVHMMKLNRTTGNYEFWEPGENRPTILWTPNEQEFKVPAHTGNEEQPFIPSQITVLPIPDKVGSDIESLPMPEEKDFRDYILVLPIPNMPPVYVYLSKPPVKPLEVDLYRNFNGRLRGGMHADHIPSAAAVKAAAKRLNPTLAPKEQNKQVKDVAAIIIPSKVHQKYSETYGGRNTPEQIARDAKDLKQAVDNNFNAIKPYLEEEGFSEQELEQAHQKIHDINQKQGLYK
    

Molecular Weight61317.03 Da

Isoelectric Point (pI)8.00

Net Charge (pH 7.0)2.46

Net Charge (pH 7.4) 1.42

Charge Density (pH 7.0) 0.0044

GRAVY Index-0.57

Hydrophobic Moment 0.72

Boman Index-0.04

Instability Index50.41

Aliphatic Index 68.49

Aromaticity 0.0754

Extinction Coeff. Reduced 61310.00

Extinction Coeff. Oxidized 61685.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0018970 VERIFIED: YES

Provenance & Taxonomy

OrganismPhotorhabdus khanii subsp. guanajuatensis [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)

PaperPhotorhabdus khanii subsp. guanajuatensis subsp. nov., isolated from Heterorhabditis atacamensis, and Photorhabdus luminescens subsp. mexicana subsp. nov., isolated from Heterorhabditis mexicana entomopathogenic nematodes PMID30688647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30688647/