MYP_032385
H-19, Hymenochirin-1B [P5K,D9K; A18,A22 S5]
Anticancer
Standard
29 amino acids
C142H263N39O37S
Standard
IKLSKETKKNLKKVLKGAIKGSIAVSKMV
3140.91 Da
10.54
7.75
7.54
0.2674
-0.10
0.69
-0.08
-5.45
117.59
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1273.61
-10.47
45.0
46.0
120.0
219.0
0.0
29.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0039901
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hymenochirin
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Stapled: Ⓧ(18) and Ⓧ (22) are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Anticancer
HCT116
1.78±0.35 μM
IC50
RECORD: Rec_0069066
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hymenochirin
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Stapled: Ⓧ(18) and Ⓧ (22) are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Anticancer
HepG2
1.64±0.36 μM
IC50
RECORD: Rec_0286715
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hymenochirin
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Stapled: Ⓧ(18) and Ⓧ (22) are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Anticancer
A549
1.00±0.36 μM
IC50