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MYP_032378
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
19 amino acids
C98H154N24O23
Standard
Sequence
FLSLIPHIVSGVASIAKHF
Physicochemical Analysis
2036.42 Da
8.76
0.93
0.63
0.0491
1.26
0.51
0.52
21.16
143.68
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
722.40
-3.63
25.0
26.0
63.0
145.0
5.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0100305 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Phylloseptin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
5.0 μM
MIC
PaperR. Zhang et al. / Molecular Immunology 47 (2010) 2030-2037. Phylloseptin-1 (PSN-1) from Phyllomedusa sauvagei skin secretion: A novel broad-spectrum antimicrobial peptide with antibiofilm activity Evidence URLhttps://www.uniprot.org/uniprotkb/E3PQH3/entry
RECORD: Rec_0101573 VERIFIED: YES
Provenance & Taxonomy
Waxy monkey [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID22345469 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22345469/
RECORD: Rec_0122714 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antibiofilm Antibacterial
Staphylococcus aureus ATCC 6538
5 μM
OD600
RECORD: Rec_0125575 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0126197 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagei [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli and Candida albicans
PMID20451254 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20451254/
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