Peptide Database

Peptide NameCyclotide vaby C

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC116H186N38O39S6

DescriptionStandard

        GLPVCGETCAGGRCNTPGCSCSWPVCTRN
    

Molecular Weight2929.34 Da

Isoelectric Point (pI)7.78

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.41

Charge Density (pH 7.0) 0.0243

GRAVY Index-0.07

Hydrophobic Moment 0.28

Boman Index0.04

Instability Index55.04

Aliphatic Index 36.90

Aromaticity 0.0345

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1215.97

LogP -19.40

H-bond Donors 48.0

H-bond Acceptors 46.0

Rotatable Bonds 86.0

Heavy Atoms 199.0

Ring Count 5.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013246 VERIFIED: NO

Provenance & Taxonomy

OrganismViola tricolor [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0319837 VERIFIED: YES

Provenance & Taxonomy

OrganismViola tricolor [Plant],Viola abyssinica [Plant]

FamilyCyclotide

Tax ID214053

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial Cytotoxic