Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC514H840N144O145S10

DescriptionStandard

        MRLFLIIAILLIQKPTETEQLKKCWGHYIQGRCRKVCRVTEIREVLCENRRYCCLNIKQLEERKKVTQPPCPRPLTFAATFASDMEEEILPSSDPPADPM
    

Molecular Weight11677.70 Da

Isoelectric Point (pI)8.52

Net Charge (pH 7.0)2.54

Net Charge (pH 7.4) 2.14

Charge Density (pH 7.0) 0.0254

GRAVY Index-0.35

Hydrophobic Moment 0.62

Boman Index-0.10

Instability Index63.81

Aliphatic Index 86.80

Aromaticity 0.0600

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4657.88

LogP -38.47

H-bond Donors 166.0

H-bond Acceptors 159.0

Rotatable Bonds 388.0

Heavy Atoms 813.0

Ring Count 17.0

Amide Bonds 106.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0386310 VERIFIED: NO

Provenance & Taxonomy

OrganismSciurus vulgaris [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence