Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length141 amino acids

Chemical FormulaC684H1095N185O202S7

DescriptionStandard

        MQISEKGLKALKSDEGCSLTAYRCPARVLTIGYGHTSGVKLGDVITEQQAEQFLLEDLAPVYITIETNVKVPLTQGQFDALCSFIFNLGAGAFVRSTLLKKLNAGDYKGAANEFMRWNMAGGRILPGLDARRASEKTMFLS
    

Molecular Weight15366.58 Da

Isoelectric Point (pI)8.46

Net Charge (pH 7.0)1.57

Net Charge (pH 7.4) 1.23

Charge Density (pH 7.0) 0.0112

GRAVY Index-0.02

Hydrophobic Moment 0.61

Boman Index0.08

Instability Index32.67

Aliphatic Index 90.71

Aromaticity 0.0851

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11585.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6235.13

LogP -60.80

H-bond Donors 219.0

H-bond Acceptors 212.0

Rotatable Bonds 518.0

Heavy Atoms 1078.0

Ring Count 18.0

Amide Bonds 151.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0035751 VERIFIED: NO

Provenance & Taxonomy

OrganismPhotorhabdus khanii subsp. guanajuatensis [Bacterium]

FamilyLysozyme

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence

PaperPhotorhabdus khanii subsp. guanajuatensis subsp. nov., isolated from Heterorhabditis atacamensis, and Photorhabdus luminescens subsp. mexicana subsp. nov., isolated from Heterorhabditis mexicana entomopathogenic nematodes PMID30688647 Evidence URLhttps://www.uniprot.org/uniprotkb/A0A4R4J540/entry