Peptide Database

Peptide NameBrevinin-2Tbe

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC354H581N95O114S5

DescriptionStandard

        MFTLKKSLLLFFFLGTISLSLCQEERNADEDDGEMTEEEKRGILDTLKNLAKTAGKGALQSLLNHASCKLSGQC
    

Molecular Weight8152.29 Da

Isoelectric Point (pI)5.26

Net Charge (pH 7.0)-2.42

Net Charge (pH 7.4) -2.76

Charge Density (pH 7.0) -0.0328

GRAVY Index-0.22

Hydrophobic Moment 0.71

Boman Index-0.01

Instability Index37.36

Aliphatic Index 91.08

Aromaticity 0.0541

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3413.61

LogP -35.69

H-bond Donors 120.0

H-bond Acceptors 118.0

Rotatable Bonds 289.0

Heavy Atoms 568.0

Ring Count 5.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012888 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax lessonae [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Amphibian defense peptide Non-hemolytic Non-ribosomal