Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length460 amino acids

Chemical FormulaC2319H3607N613O635S12

DescriptionStandard

        TNPGFVVRITQAGLDYAHQHGIAVLQKELAQLKLPDISGDFRVRHLGKVHYEISSLNLRDFHLPYSRISLVPNVGLQVAISNAFAEVDGNWRVKFHFIRDHGSFNLEVKNVYIKIDLKLGSDTSGKPTVSTSACSTRISSVHVHFSGKFGWLYNLFYSAVESRFRKILEGKVCDSVVSSVSGDLQRYLQTLPVTAKIDAKAGIDYSLVAPPVATAQTLDVDLKGEFFSLAHRGAVPFHPPVLAFPPDHDRMVYFGASSYFFNTAGFAYHAAGALVFEITDSMVRRAGGSVLPWMCHGSFPLPAPLQLDKMYPNMLMKLRLSAPSAPFLSIAPDGISLQPTVDIQAYAILPSSSLAPLFLLSLVSNVSATVDVKSGHIVGNLMSGHLVKLFSFPLPPQLQVRMLQSIMNIYASSILLPRVNERLAEGFPLPLPDRIQLSNILVQFHQNFLLLGADVHYTPR
    

Molecular Weight50618.95 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)6.96

Net Charge (pH 7.4) 5.73

Charge Density (pH 7.0) 0.0151

GRAVY Index0.17

Hydrophobic Moment 0.67

Boman Index0.16

Instability Index40.49

Aliphatic Index 102.35

Aromaticity 0.1000

Extinction Coeff. Reduced 38850.00

Extinction Coeff. Oxidized 38975.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239845 VERIFIED: NO

Provenance & Taxonomy

OrganismOdontophorus gujanensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria