Peptide Database

Peptide NameMacromomycin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length148 amino acids

Chemical FormulaC640H1037N175O212S3

DescriptionStandard

        MTVKNKLGLATRITAATAVAAGLALAVQPSALAAATAPVVSVSPASGLTDGQQVTVTATGLTPNTVFHLGHCAFVEPEKYGCDATTAKDVVSDASGKVNTTITVHSSFEAVVTSDGAVWGTVDAKKTQTQVGLGSDAGEGGGQPVTFK
    

Molecular Weight14671.32 Da

Isoelectric Point (pI)5.82

Net Charge (pH 7.0)-2.25

Net Charge (pH 7.4) -2.67

Charge Density (pH 7.0) -0.0152

GRAVY Index0.21

Hydrophobic Moment 0.44

Boman Index0.19

Instability Index18.79

Aliphatic Index 83.72

Aromaticity 0.0405

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6105.64

LogP -80.74

H-bond Donors 212.0

H-bond Acceptors 216.0

Rotatable Bonds 471.0

Heavy Atoms 1030.0

Ring Count 16.0

Amide Bonds 156.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0087641 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptomyces sp. PKU-MA01144 [Bacterium]

FamilyNeocarzinostatin

Tax ID2729138

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal