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MYP_032150
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Basic Information
Puroindoline-A (34-46)-K-Puroindoline-A (34-46)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
27 amino acids
C202H256N48O30
Standard
Sequence
FPVTWRWWKWWKGKFPVTWRWWKWWKG
Physicochemical Analysis
3836.50 Da
12.00
6.76
6.54
0.2502
-1.07
0.46
0.04
53.74
21.48
0.4444
55000.00
55000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1254.60
5.25
49.0
37.0
107.0
280.0
24.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0300257 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Sheep erythrocytes: No hemolysis up tp 500 μg/ml
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
RECORD: Rec_0342120 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
NIH 3T3
250 μg/mL
IC50
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
RECORD: Rec_0347823 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
250 μg/mL
MIC
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
RECORD: Rec_0395024 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HeLa
32 μg/mL
IC50
PMID33207639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33207639/
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