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MYP_032098
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Basic Information
Ctn[1-14]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
14 amino acids
C88H148N24O16
Standard
Sequence
KRFKKFFKKVKKSV
Physicochemical Analysis
1798.27 Da
11.47
7.75
7.54
0.5538
-1.13
0.81
-0.53
2.98
41.43
0.2143
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
705.89
-3.10
26.0
24.0
68.0
128.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0254033 VERIFIED: YES
Provenance & Taxonomy
Rattlesnake Venom Cathelicidin [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HeLa S3
1 μM
IC50
PaperPubMed PMID: 26465972 PMID26465972 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26465972/
RECORD: Rec_0275198 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus aureus ATCC 29213 and a clinical isolate
71 μM
MIC
Serum 21 min
PaperStructural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity.
RECORD: Rec_0278755 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
T-rubrum LABMIC 0203 or 0204
>40 μM
MIC
Serum 21 min
PaperStructural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity.
RECORD: Rec_0291667 VERIFIED: YES
Provenance & Taxonomy
Crotalus durissus terrificus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
Cryptococcus neoformans LABMIC 0406
10 μg/mL
MIC
PMID31626724 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31626724/
RECORD: Rec_0295573 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Escherichia coli ATCC 25922 and a clinical isolate
71 μM
MIC
Serum 21 min
PaperStructural Dissection of Crotalicidin, a Rattlesnake Venom Cathelicidin, Retrieves a Fragment with Antimicrobial and Antitumor Activity.
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