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MYP_032040
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Basic Information
Cathelicidin-6 (Antibacterial peptide BMAP-27, Myeloid antib
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
27 amino acids
C160H265N45O29
Standard
Sequence
GRFKRFRKKFKKLFKKLSPVIPLLHLG
Physicochemical Analysis
3283.10 Da
12.00
9.84
9.58
0.3645
-0.37
0.82
-0.18
21.06
97.41
0.1481
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1219.09
-4.17
44.0
40.0
115.0
234.0
7.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0288433 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
10 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/8910461/ PMID8910461 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8910461/
RECORD: Rec_0295021 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
cathelicidin family
9913; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial cathelicidin family Antibacterial Antifungal Host defense
PaperPDB 2KET structural record; NMR; chain A; residues 1-26
RECORD: Rec_0304456 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Cathelicidin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus ATCC 25923
2 μg/mL
MIC
PMID8910461;19136450 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8910461/
RECORD: Rec_0322642 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Cathelicidin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML35
1 μM
MIC
PMID8910461;29103679 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8910461/
RECORD: Rec_0325900 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Cathelicidin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus methicillin-resistant Staphylococcus aureus
4 μM
MIC
PMID8910461;29103679 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8910461/
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