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MYP_032016
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Basic Information
Unnamed
Antimicrobial
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
27 amino acids
C120H202N34O31
Standard
Sequence
GLASFLGKALKAGLKIGAHLLGGAPQQ
Physicochemical Analysis
2617.10 Da
10.30
2.84
2.59
0.1053
0.46
0.62
0.31
13.59
119.63
0.0370
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1024.28
-9.16
34.0
35.0
89.0
185.0
3.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0035186 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 22.2%, E 0.0%, T 55.6%, C 22.2% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0039653 VERIFIED: YES
Provenance & Taxonomy
Xenopus clivii [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial
PMID21199684 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21199684/
RECORD: Rec_0147532 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0251344 VERIFIED: NO
Provenance & Taxonomy
Xenopus ruwenzoriensis [Animal]
Gastrin cholecystokinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal
Qualitative functional evidence
PMID27290612 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27290612/; https://www.uniprot.org/uniprotkb/C0HKN1/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0361240 VERIFIED: NO
Provenance & Taxonomy
Xenopus laevis [Animal] [Animal]; Xenopus victorianus [Animal] [Animal]; Xenopus laevis sudanesis [Animal] [Animal]; Xenopus ruwenzoriensis [Animal]
8355
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone
B cell line, BD11