Peptide Database

Peptide NameNeurotoxin alpha-KTx 28.1

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC118H193N31O41S7

DescriptionStandard

        ACVTHEDCTLLCYDTIGTCVDGKCKCM
    

Molecular Weight2926.43 Da

Isoelectric Point (pI)4.66

Net Charge (pH 7.0)-2.17

Net Charge (pH 7.4) -2.51

Charge Density (pH 7.0) -0.0805

GRAVY Index0.34

Hydrophobic Moment 0.36

Boman Index0.11

Instability Index39.80

Aliphatic Index 68.52

Aromaticity 0.0370

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1150.99

LogP -12.95

H-bond Donors 46.0

H-bond Acceptors 47.0

Rotatable Bonds 95.0

Heavy Atoms 197.0

Ring Count 2.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0129374 VERIFIED: YES

Provenance & Taxonomy

OrganismIsometrus maculatus [Animal]

FamilyPotassium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-19; 8-24; 12-26

Bio-Activity Profile

Function

Toxin Venom Potassium channel inhibitor family