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MYP_031947
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Basic Information
Grammistin PpIIb (Group II grammistin; fish, chordates, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
13 amino acids
C76H119N15O15
Standard
Sequence
FIGGIISFIKKLF
Physicochemical Analysis
1482.85 Da
10.00
1.76
1.55
0.1352
1.60
0.58
0.61
-0.87
150.00
0.2308
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
484.79
0.69
17.0
17.0
50.0
106.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0259254 VERIFIED: NO
Provenance & Taxonomy
Grammistes sexlineatus [Animal]
Grammistin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic Non-ribosomal
Gram-negative bacteria; Gram-positive bacteria
Qualitative functional evidence
PMID15777955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15777955/; https://www.uniprot.org/uniprotkb/P69841/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0271184 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0308033 VERIFIED: YES
Provenance & Taxonomy
Pogonoperca punctata [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium S1
50 μg/mL
MIC
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP02320
RECORD: Rec_0312889 VERIFIED: YES
Provenance & Taxonomy
Pogonoperca punctata [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Has hemolytic activity
Hemolysis
Evidence URLhttps://www.uniprot.org/uniprotkb/P69844/entry
RECORD: Rec_0316578 VERIFIED: YES
Provenance & Taxonomy
Pogonoperca punctata [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Aeromonas salmonicida NCIBM 1102
50 μg/mL
MIC
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP02320
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