Peptide Database

Peptide Nameomega-Conotoxin PuIIA

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC133H206N42O39S6

DescriptionStandard

        TCNTPTQYCTLHRHCCSLYCHKTIHACA
    

Molecular Weight3209.71 Da

Isoelectric Point (pI)8.30

Net Charge (pH 7.0)1.68

Net Charge (pH 7.4) 1.20

Charge Density (pH 7.0) 0.0602

GRAVY Index-0.21

Hydrophobic Moment 0.41

Boman Index-0.02

Instability Index59.95

Aliphatic Index 48.93

Aromaticity 0.0714

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1290.89

LogP -16.06

H-bond Donors 52.0

H-bond Acceptors 51.0

Rotatable Bonds 97.0

Heavy Atoms 220.0

Ring Count 7.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0087827 VERIFIED: NO

Provenance & Taxonomy

OrganismConus pulicarius [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-16; 9-20; 15-27

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0401987 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic