Peptide Database

Peptide NameDermatoxin-DA1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC379H614N98O114S3

DescriptionStandard

        MAFLKKSLFLVLFLGLVPLFLCENEKREGENEKEENDDQSEEKRSLGSFMKGVGKGLATVGKIVADQFGKLLEAGKG
    

Molecular Weight8463.71 Da

Isoelectric Point (pI)5.45

Net Charge (pH 7.0)-1.49

Net Charge (pH 7.4) -1.75

Charge Density (pH 7.0) -0.0193

GRAVY Index-0.25

Hydrophobic Moment 0.63

Boman Index0.01

Instability Index27.43

Aliphatic Index 89.87

Aromaticity 0.0779

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3451.63

LogP -29.69

H-bond Donors 117.0

H-bond Acceptors 116.0

Rotatable Bonds 303.0

Heavy Atoms 594.0

Ring Count 7.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0102022 VERIFIED: NO

Provenance & Taxonomy

OrganismAgalychnis dacnicolor [Animal]

FamilyFrog skin active peptide (FSAP)

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence