Peptide Database

Peptide NameFragment 1 of A disintegrin and metalloproteinase with thrombospondin motifs 4

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC34H56N10O10S

DescriptionStandard

        TLRSFCA
    

Molecular Weight796.93 Da

Isoelectric Point (pI)7.91

Net Charge (pH 7.0)0.39

Net Charge (pH 7.4) 0.18

Charge Density (pH 7.0) 0.0555

GRAVY Index0.70

Hydrophobic Moment 0.50

Boman Index0.06

Instability Index98.86

Aliphatic Index 70.00

Aromaticity 0.1429

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 340.28

LogP -3.82

H-bond Donors 14.0

H-bond Acceptors 12.0

Rotatable Bonds 24.0

Heavy Atoms 55.0

Ring Count 1.0

Amide Bonds 6.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0169914 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-converting enzyme

Activity2 μM

MethodIC50