Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length109 amino acids

Chemical FormulaC514H852N142O147S14

DescriptionStandard

        MKSLMFTLAVFMLLTQLVSGNWFTKKCANKTGLCKKKCKPGEVYAEPAWVMCGKASVCCVPGKKRSGHPSVYVEKKTTRRSTATTARSLMMNTTTLMSSMAATPVSATS
    

Molecular Weight11822.04 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)13.52

Net Charge (pH 7.4) 13.14

Charge Density (pH 7.0) 0.1240

GRAVY Index-0.05

Hydrophobic Moment 0.54

Boman Index0.02

Instability Index40.05

Aliphatic Index 61.74

Aromaticity 0.0642

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4638.76

LogP -52.35

H-bond Donors 173.0

H-bond Acceptors 176.0

Rotatable Bonds 394.0

Heavy Atoms 817.0

Ring Count 15.0

Amide Bonds 112.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0173300 VERIFIED: NO

Provenance & Taxonomy

OrganismAotus nancymaae [Animal]

FamilyDefensin

Tax ID37293

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence