Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length285 amino acids

Chemical FormulaC1426H2217N379O402S6

DescriptionStandard

        RASGSFDLEVENVYIKINLKLGSDTSGKPTIDASDCSTRISKVRVHFSGRFGWIYNLFHSAVESRFRKILESKVCDSAVTSVRRELQPYLQTLPVTARIDSVAGIDYSLVAPPTATARSLDVALKGEFFSLANRSSVPFFPPALGLPPDHDRMVYFGVSSYFFNTAGFTYHAARALVFEITNSMIPKGFDFHLNTSTFSAFIPQLEKLYPNMQMKFRLSAPSAPFLNIGPGGLSLRPVVDIQAYAILPNSSLAPLFLLSLTGNVSAVIDVRSGHIVGNLTVGRYR
    

Molecular Weight31294.54 Da

Isoelectric Point (pI)9.46

Net Charge (pH 7.0)7.28

Net Charge (pH 7.4) 6.69

Charge Density (pH 7.0) 0.0255

GRAVY Index0.11

Hydrophobic Moment 0.60

Boman Index0.12

Instability Index36.84

Aliphatic Index 93.05

Aromaticity 0.1123

Extinction Coeff. Reduced 20400.00

Extinction Coeff. Oxidized 20525.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240165 VERIFIED: NO

Provenance & Taxonomy

OrganismSyrrhaptes paradoxus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria