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MYP_031830
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Basic Information
K29
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Standard
29 amino acids
C141H210N40O38S5
Standard
Sequence
FGGASCCLYCRCHIDHPNPKGFCDLKGKY
Physicochemical Analysis
3233.75 Da
8.40
1.88
1.50
0.0649
-0.32
0.31
0.00
48.20
43.79
0.1379
2980.00
3230.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1236.24
-11.90
47.0
47.0
101.0
224.0
8.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0178386 VERIFIED: YES
Provenance & Taxonomy
Severe acute respiratory syndrome-related coronavirus [Virus]
nsp10-derived peptide
694009
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
160 μM
IC50
PaperShort peptides derived from the interaction domain of SARS coronavirus nonstructural protein nsp10 can suppress the 2'-O-methyltransferase activity of nsp10/nsp16 complex PMID22659295 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22659295/
RECORD: Rec_0276721 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 34.5%, E 0.0%, T 37.9%, C 27.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0363403 VERIFIED: YES
Provenance & Taxonomy
Severe acute respiratory syndrome-related coronavirus [Virus]
Virus-derived peptide
694009;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Replication inhibitor
SARS coronavirus (Replication); Escherichia coli
160 μM
MTase Activity assay
PaperShort peptides derived from the interaction domain of SARS coronavirus nonstructural protein nsp10 can suppress the 2'-O-methyltransferase activity of nsp10/nsp16 complex. | Ke M, Chen Y, Wu A, Sun Y, Su C, Wu H, Jin X, Tao J, Wang Y, Ma X, Pan JA, Guo D. | Virus Res. 2012 | PMID:22659295 PMID22659295 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22659295/