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MYP_031827
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Basic Information
H1C
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
43 amino acids
C197H304N50O62S2
Standard
Sequence
MSGIVEAISNAVKSGLDHDWVNMGTSIADVVAKGADFIAGFFS
Physicochemical Analysis
4428.95 Da
4.35
-3.41
-3.68
-0.0792
0.53
0.62
0.31
1.77
93.02
0.0930
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1776.09
-18.41
61.0
62.0
145.0
311.0
6.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029280 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus cohnii subsp. cohnii [Bacterium]
74704.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cytotoxic
Rabbit erythrocytes
28070±3060 μM
PaperMak P, Maszewska A, Rozalska M. The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. FEMS Microbiol Lett. 2008 Oct;287(2):230-235. doi:10.1111/j.1574-6968.2008.01321.x. PMID18752624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18752624/
RECORD: Rec_0120318 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus cohnii subsp. cohnii [Bacterium]
74704.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cytotoxic
Guinea-pig erythrocytes
4230±1060 μM
PaperMak P, Maszewska A, Rozalska M. The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. FEMS Microbiol Lett. 2008 Oct;287(2):230-235. doi:10.1111/j.1574-6968.2008.01321.x. PMID18752624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18752624/
RECORD: Rec_0178934 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus cohnii subsp. cohnii [Bacterium]
74704.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cytotoxic
Human erythrocytes
3320±120 μM
PaperMak P, Maszewska A, Rozalska M. The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. FEMS Microbiol Lett. 2008 Oct;287(2):230-235. doi:10.1111/j.1574-6968.2008.01321.x. PMID18752624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18752624/
RECORD: Rec_0250051 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus cohnii subsp. cohnii [Bacterium]
74704.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cytotoxic
Dog erythrocytes
4370±600 μM
PaperMak P, Maszewska A, Rozalska M. The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. FEMS Microbiol Lett. 2008 Oct;287(2):230-235. doi:10.1111/j.1574-6968.2008.01321.x. PMID18752624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18752624/
RECORD: Rec_0264927 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus cohnii subsp. cohnii [Bacterium]
74704.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cytotoxic
Sheep erythrocytes
7530±190 μM
PaperMak P, Maszewska A, Rozalska M. The amino acid sequences and activities of synergistic hemolysins from Staphylococcus cohnii. FEMS Microbiol Lett. 2008 Oct;287(2):230-235. doi:10.1111/j.1574-6968.2008.01321.x. PMID18752624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18752624/
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