Peptide Database

Peptide NameBeta-defensin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC218H341N65O64S6

DescriptionStandard

        GNFLTGLGHRSDHYNCISSGGQCLYSACPIFTKIQGTCYRGKAKCCK
    

Molecular Weight5088.83 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)4.87

Net Charge (pH 7.4) 4.47

Charge Density (pH 7.0) 0.1036

GRAVY Index-0.28

Hydrophobic Moment 0.49

Boman Index0.00

Instability Index32.90

Aliphatic Index 54.04

Aromaticity 0.1064

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2090.33

LogP -26.31

H-bond Donors 80.0

H-bond Acceptors 77.0

Rotatable Bonds 167.0

Heavy Atoms 353.0

Ring Count 8.0

Amide Bonds 50.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0365575 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal