Peptide Database

Peptide NameAmercin

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC172H250N52O51S6

DescriptionStandard

        GFGCPFNQYQCHSHCLSIGRRGGYCGGSFKTTCTCYN
    

Molecular Weight4054.53 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)2.87

Net Charge (pH 7.4) 2.47

Charge Density (pH 7.0) 0.0776

GRAVY Index-0.39

Hydrophobic Moment 0.50

Boman Index0.02

Instability Index50.35

Aliphatic Index 21.08

Aromaticity 0.1622

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1663.74

LogP -22.99

H-bond Donors 65.0

H-bond Acceptors 62.0

Rotatable Bonds 126.0

Heavy Atoms 281.0

Ring Count 9.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0286825 VERIFIED: YES

Provenance & Taxonomy

OrganismAmblyomma americanum [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0292952 VERIFIED: YES

Provenance & Taxonomy

OrganismAmblyomma americanum [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)