Peptide Database

Peptide NamePotassium channel toxin Tx15

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC166H267N47O51S7

DescriptionStandard

        GKFGKCKPNICAKTCQTEKGKGMGYCNKTECVCSEW
    

Molecular Weight3961.64 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)3.70

Net Charge (pH 7.4) 3.39

Charge Density (pH 7.0) 0.1028

GRAVY Index-0.74

Hydrophobic Moment 0.32

Boman Index-0.14

Instability Index32.15

Aliphatic Index 21.67

Aromaticity 0.0833

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1613.28

LogP -19.35

H-bond Donors 61.0

H-bond Acceptors 62.0

Rotatable Bonds 136.0

Heavy Atoms 271.0

Ring Count 5.0

Amide Bonds 38.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0066673 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus serrulatus [Animal]

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-26, 11-31, 15-33

Bio-Activity Profile

Function

Toxin

Activity0.196 μM

MethodIC50

RECORD: Rec_0114665 VERIFIED: YES