Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length205 amino acids

Chemical FormulaC1047H1603N233O314S10

DescriptionStandard

        KIVSVVFVIFCVLPTTLTAVMQIDDWAEVDYSLSSLPAVFQQFIDLDLKGKVFPAGNYTDSPYMAASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTTGAFNMTIAEETCSYFNINTEIFGSIIPEVIKYSVTPYPVMLKLMSTEIPIISLQQDSFTLEVQGSVEVLAVLPDSTTQSLFTLNIAANTSISLNIFDKKLMGSLCLNR
    

Molecular Weight22798.95 Da

Isoelectric Point (pI)4.07

Net Charge (pH 7.0)-12.25

Net Charge (pH 7.4) -12.54

Charge Density (pH 7.0) -0.0598

GRAVY Index0.41

Hydrophobic Moment 0.58

Boman Index0.26

Instability Index42.10

Aliphatic Index 99.37

Aromaticity 0.1317

Extinction Coeff. Reduced 20400.00

Extinction Coeff. Oxidized 20525.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267025 VERIFIED: NO

Provenance & Taxonomy

OrganismBrachypodius atriceps [Plant]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria