Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length381 amino acids

Chemical FormulaC1931H3015N513O544S8

DescriptionStandard

        SNPGFVVRITQAGLDYAHQQGIAILEKELAQLTLPDISGDFRVMRVGKVHYELSRLRLRSFHLPYSRISPVPNVGLQVSISNAFAELDGNWRVKLFFIRDHGSFDLKVENIYIKISLRLGSDATGKPTISTSDCNTRISKVRVLFSGKFAWLYNLFHSAIEQRFRKILESKVCATVTESVHNELQTYIRTLPVTARIDAMAGIDYSLVAPPTATAQSLDTELKGEFYSLAHRSTVPFSPLPLSFPSDHDRMVYFGASSYFFNTAGFAYHTAGALVFEITDAMIPKDVDFHLNTSVFSAFVPQLEQMYPNTPMKLRLSTFTAPFLNIGPEGISLKPVVDVQAYAILPNSSLVPLFVLSLVRNVSAVIDVRSGHIVGRLDVGR
    

Molecular Weight42377.23 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)4.43

Net Charge (pH 7.4) 3.56

Charge Density (pH 7.0) 0.0116

GRAVY Index0.10

Hydrophobic Moment 0.68

Boman Index0.11

Instability Index37.40

Aliphatic Index 98.74

Aromaticity 0.1050

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0053193 VERIFIED: NO

Provenance & Taxonomy

OrganismCalyptomena viridis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria