Peptide Database

Peptide NameDefensin-5-like (neutrophil antibiotic peptide NP-1-like)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC445H723N129O141S8

DescriptionStandard

        MKTFALLAAILLLALQAQSDPLPATVEEASAQEQMEEVDPITTISITGEESSDLRDAGLRAGVNCYCRRGGCNFRERRIGTCLYRGIYYNLCCR
    

Molecular Weight10392.80 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-2.54

Net Charge (pH 7.4) -2.86

Charge Density (pH 7.0) -0.0270

GRAVY Index-0.09

Hydrophobic Moment 0.84

Boman Index-0.01

Instability Index54.43

Aliphatic Index 90.43

Aromaticity 0.0638

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4379.05

LogP -47.01

H-bond Donors 160.0

H-bond Acceptors 147.0

Rotatable Bonds 346.0

Heavy Atoms 723.0

Ring Count 9.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0040621 VERIFIED: NO

Provenance & Taxonomy

OrganismCastor canadensis [Animal]

FamilyDefensin

Tax ID51338

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal