Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC779H1227N201O244S15

DescriptionStandard

        MNILMLTFIICGLLTQVTKGSFEPPKCWKNNIGHCRRRCLDTERYILLCRNKLSCCIYIIISHEYTRRPAFPMIHLEDITFDYSDVDSFTGSPVSMLNDLITFDTTKFGETMTPETNTPETTMPPSETTTPETTMPPSETATSETMPPLSQTALTHN
    

Molecular Weight17793.25 Da

Isoelectric Point (pI)5.12

Net Charge (pH 7.0)-6.19

Net Charge (pH 7.4) -6.75

Charge Density (pH 7.0) -0.0394

GRAVY Index-0.27

Hydrophobic Moment 0.60

Boman Index0.03

Instability Index69.20

Aliphatic Index 69.55

Aromaticity 0.0764

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7062.41

LogP -74.14

H-bond Donors 250.0

H-bond Acceptors 257.0

Rotatable Bonds 567.0

Heavy Atoms 1239.0

Ring Count 31.0

Amide Bonds 165.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0301038 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0328788 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Tax ID9598

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence