Peptide Database

Peptide NameNeurosecretory protein VGF [Cleaved into: Neuroendocrine regulatory peptide-1 (NERP-1); Neuroendocrine regulatory peptide-2 (NERP-2); VGF-derived peptide TLQP-21; VGF-derived peptide TLQP-62]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length617 amino acids

Chemical FormulaC2945H4631N883O981S4

DescriptionStandard

        MKTFTLPASVLFCFLLLIQGLGAAPPGRPDVFPPPLSSEHNGQVAEDAVSRPKDDGVPEVRAARNPEPQDQGELFQGVDPRALASVLLQALDRPASPPSVPGGSQQGTPEEAAEALLTESVRSQTHSLPAPEIQAPAVAPPRPQTQDRDPEEDDRSEELEALASLLQELRDFSPSNAKRQQETAAAETETRTHTLTRVNLESPGPERVWRASWGEFQARVPERAPLPPPVPSQFQARMSESAPLPETHQFGEGVSSPKTHLGETLTPLSKAYQSLGGPFPKVRRLEGSFLGGSEAGERLLQQGLAQVEAGRRQAEATRQAAAQEERLADLASDLLLQYLLQGGARQRDLGGRELQETQQERENEREEEAEQERRGGGEDDVGEEDEEAAEAEAEAEEAERARQNALLFAEEEDGEAGAEDKRSQEEAPGHRRKDAEGAEEGGEEDDDDEEMDPQTIDSLIELSTKLHLPADDVVSIIEEVEEKRKRKKNAPPEPVPPPRAAPAPTHVRSPQPPPPAPARDELPDWNEVLPPWDREEDEVFPPGPYHPFPNYIRPRTLQPPASSRRRHFHHALPPARHHPDLEAQARRAQEEADAEERRLQEQEELENYIEHVLLHRP
    

Molecular Weight68230.87 Da

Isoelectric Point (pI)4.65

Net Charge (pH 7.0)-55.84

Net Charge (pH 7.4) -57.08

Charge Density (pH 7.0) -0.0905

GRAVY Index-0.98

Hydrophobic Moment 0.63

Boman Index-0.19

Instability Index84.13

Aliphatic Index 65.28

Aromaticity 0.0389

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 29450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0138467 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Proteolytic Non-hemolytic

TargetNo Target Organism Found

PaperLineage-specific biology revealed by a finished genome assembly of the mouse; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID19468303;15489334;19863797;21183079;22289198;25456411;25917832;26180209;30504797 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19468303/