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MYP_031472
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
2 amino acids
C12H16N2O5
Standard
Sequence
SY
Physicochemical Analysis
268.27 Da
5.24
-0.54
-0.75
-0.2705
-1.05
0.17
0.04
5.00
0.00
0.5000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
132.88
-1.18
5.0
5.0
6.0
19.0
1.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0318709 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
66.3
IC50
PaperMeisel H., Walsh D. J., Murray B., FitzGerald R. J.. ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
RECORD: Rec_0320277 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Glycine max [Plant]; Sus scrofa [Animal]; Gallus gallus [Animal]; Insecta [Animal]; Poaceae [Plant]; Fabaceae [Plant]
9913; 3847; 9823; 9031; 50557; 4479; 3803
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperWhat are the ideal properties for functional food peptides with antihypertensive effect? A computational peptidology approach PMID23871047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23871047/
RECORD: Rec_0332538 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
ACE-inhibitory peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperBovine kappa-casein variants result in different angiotensin I converting enzyme (ACE) inhibitory peptides
RECORD: Rec_0335934 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
kappa-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
41 μM
IC50
PaperCharacterization of New Milk-derived Inhibitors of Angiotensin Converting Enzyme In Vitro and In Vivo | Fuglsang, A. et al. | DOI: 10.1080/1475636031000138723 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
RECORD: Rec_0339343 VERIFIED: YES
Provenance & Taxonomy
Allium sativum [Plant]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Neuropeptide ACE inhibitory
Angiotensin-converting enzyme
66300000 μM
IC50
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