Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC925H1408N210O289S8

DescriptionStandard

        QIDDLAEVDYSLSSLPEVFQPFIELDLKGVVFPAGNYTDSPYVPASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNTTIAEETCSYFNINTEIFGSIIPEVAKYSVTPNPVMLKLMATEIPIISLEQDSFTVEIRGSMEVLAVLPDSTTQSLFTMNIAANASISLNIFDQKLMGSLCLNR
    

Molecular Weight20350.83 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-16.23

Net Charge (pH 7.4) -16.51

Charge Density (pH 7.0) -0.0882

GRAVY Index0.23

Hydrophobic Moment 0.55

Boman Index0.22

Instability Index48.79

Aliphatic Index 92.77

Aromaticity 0.1250

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7919.97

LogP -87.56

H-bond Donors 268.0

H-bond Acceptors 281.0

Rotatable Bonds 651.0

Heavy Atoms 1432.0

Ring Count 34.0

Amide Bonds 199.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0364481 VERIFIED: NO

Provenance & Taxonomy

OrganismMohoua ochrocephala [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria