Peptide Database

Peptide NameTrastuzumab

Function Ontology

Anticancer

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length214 amino acids

Chemical FormulaC1032H1603N277O335S6

DescriptionStandard

        DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
    

Molecular Weight23442.81 Da

Isoelectric Point (pI)7.76

Net Charge (pH 7.0)0.99

Net Charge (pH 7.4) 0.50

Charge Density (pH 7.0) 0.0046

GRAVY Index-0.45

Hydrophobic Moment 0.58

Boman Index-0.02

Instability Index54.43

Aliphatic Index 64.67

Aromaticity 0.0981

Extinction Coeff. Reduced 25900.00

Extinction Coeff. Oxidized 26150.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0249760 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Cricetulus griseus [Animal]

FamilyMonoclonal antibody

Tax ID9606;10029

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsLipidation

Bio-Activity Profile

Function

Anticancer Immunomodulatory Hormone replacement Enzyme replacement

TargetCHO

Half-Lifeaverage 28.5 days

RECORD: Rec_0261614 VERIFIED: NO