Peptide Database

Peptide NameIndolicidin [P10A]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC98H129N25O14

DescriptionStandard

        ILPWKWPWWAWRR
    

Molecular Weight1881.23 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.2122

GRAVY Index-0.81

Hydrophobic Moment 0.47

Boman Index0.06

Instability Index66.93

Aliphatic Index 67.69

Aromaticity 0.3846

Extinction Coeff. Reduced 27500.00

Extinction Coeff. Oxidized 27500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 623.71

LogP 3.62

H-bond Donors 24.0

H-bond Acceptors 17.0

Rotatable Bonds 49.0

Heavy Atoms 137.0

Ring Count 12.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0347982 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity15.6 μM

MethodHemolysis

RECORD: Rec_0388637 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetSalmonella typhimurium

Activity50 μM

MethodMIC

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