Peptide Database

Peptide NameDefensin-C

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC462H737N135O140S9

DescriptionStandard

        MRTLTVVCFVALCLSAIFTTGNALPGELADDVRPYANSLFDELPEESYQAAVENFRLKRATCDLLSGFGVGDSACAAHCIARRNRGGYCNAKKVCVCRN
    

Molecular Weight10711.20 Da

Isoelectric Point (pI)7.51

Net Charge (pH 7.0)0.52

Net Charge (pH 7.4) 0.12

Charge Density (pH 7.0) 0.0053

GRAVY Index0.11

Hydrophobic Moment 0.61

Boman Index0.03

Instability Index37.94

Aliphatic Index 83.84

Aromaticity 0.0808

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4428.31

LogP -49.30

H-bond Donors 163.0

H-bond Acceptors 151.0

Rotatable Bonds 349.0

Heavy Atoms 746.0

Ring Count 12.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0398827 VERIFIED: YES

Provenance & Taxonomy

OrganismAedes aegypti [Animal]

FamilyDefensin

Tax ID7159

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-Gram-positive Non-hemolytic

TargetGram Positive Bacteria