Peptide Database

Peptide NameRibonuclease K6 (RNase K6) (EC 3.1.27.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length150 amino acids

Chemical FormulaC777H1206N216O202S13

DescriptionStandard

        MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMIGINNYTQHCKHQNTFLHDSFQNVAAVCDLLSIVCKNRRHNCHQSSKPVNMTDCRLTSGKYPQCRYSAAAQYKFFIVACDPPQKSDPPYKLVPVHLDSIL
    

Molecular Weight17222.06 Da

Isoelectric Point (pI)9.09

Net Charge (pH 7.0)8.18

Net Charge (pH 7.4) 7.34

Charge Density (pH 7.0) 0.0545

GRAVY Index-0.10

Hydrophobic Moment 0.56

Boman Index0.06

Instability Index53.66

Aliphatic Index 90.33

Aromaticity 0.0933

Extinction Coeff. Reduced 23950.00

Extinction Coeff. Oxidized 24575.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6617.11

LogP -55.43

H-bond Donors 231.0

H-bond Acceptors 232.0

Rotatable Bonds 546.0

Heavy Atoms 1208.0

Ring Count 39.0

Amide Bonds 167.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0379027 VERIFIED: YES

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyPancreatic ribonuclease

Tax ID9595

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic

TargetE. faecium (Gram-positive)

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