Peptide Database

Peptide NameLantibiotic; gallidermin nisin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC233H355N59O85S8

DescriptionStandard

        MLETNEMLDIDLEIDIDAMPTDSDSAPQITSWSFCTGGCTSRGGGSFCSWCC
    

Molecular Weight5599.18 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-8.53

Net Charge (pH 7.4) -8.83

Charge Density (pH 7.0) -0.1641

GRAVY Index-0.04

Hydrophobic Moment 0.41

Boman Index0.13

Instability Index53.98

Aliphatic Index 56.35

Aromaticity 0.0769

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2287.96

LogP -28.81

H-bond Donors 84.0

H-bond Acceptors 85.0

Rotatable Bonds 179.0

Heavy Atoms 385.0

Ring Count 8.0

Amide Bonds 53.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0167160 VERIFIED: NO

Provenance & Taxonomy

OrganismActinobaculum sp. oral taxon 183 str. F0552 [Bacterium]

FamilyLantibiotic

Tax ID1227261

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Non-hemolytic Non-ribosomal