Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC320H506N80O84S8

DescriptionStandard

        MKPHCTLLLVLLVILALHSKGNEAVSFPWSCAALSGVCRQGACLPSELYFGPLGCGKGSLCCVSYFL
    

Molecular Weight7074.45 Da

Isoelectric Point (pI)8.22

Net Charge (pH 7.0)1.61

Net Charge (pH 7.4) 1.18

Charge Density (pH 7.0) 0.0240

GRAVY Index0.84

Hydrophobic Moment 0.45

Boman Index0.34

Instability Index37.25

Aliphatic Index 110.60

Aromaticity 0.0896

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2524.95

LogP -19.75

H-bond Donors 94.0

H-bond Acceptors 96.0

Rotatable Bonds 223.0

Heavy Atoms 492.0

Ring Count 13.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0100545 VERIFIED: NO

Provenance & Taxonomy

OrganismIctalurus punctatus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic