Peptide Database

Peptide NameKisspeptin-13

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Reproductive neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC78H106N20O19

DescriptionStandard

        LPNYNWNSFGLRF
    

Molecular Weight1627.80 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0584

GRAVY Index-0.52

Hydrophobic Moment 0.31

Boman Index0.09

Instability Index40.38

Aliphatic Index 60.00

Aromaticity 0.3077

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 651.15

LogP -4.51

H-bond Donors 22.0

H-bond Acceptors 20.0

Rotatable Bonds 47.0

Heavy Atoms 117.0

Ring Count 6.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0047862 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyKisspeptin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other Mods4:Phosphotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Growth regulation Development regulation Receptor modulation ACE inhibitory

Targetcoupled receptor

Half-LifeMammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0060341 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyKisspeptin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other Mods4:Phosphotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Growth regulation Development regulation Receptor modulation ACE inhibitory

Half-LifeMammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0404557 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 46.2%, E 0.0%, T 15.4%, C 38.5% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication

RECORD: Rec_0409571 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyKISS1

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsTyr4 Phosphotyrosine

Bio-Activity Profile

Function

Hormone Reproductive neuropeptide