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MYP_031241
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Basic Information
RL2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
18 amino acids
C100H174N32O21S2
Standard
Sequence
RLRLWRLRLCTKSIPPIC
Physicochemical Analysis
2224.78 Da
11.54
4.74
4.51
0.2633
0.09
0.59
-0.18
71.21
130.00
0.0556
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
870.31
-4.93
35.0
28.0
71.0
155.0
4.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010091 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
10-18
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922 or UB1005 or K88 or K99 strains
4-8 μM
MIC
PaperBinding loop of sunflower trypsin inhibitor 1 serves as a design motif for proteolysis-resistant antimicrobial peptides.
RECORD: Rec_0015156 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. pullorum 7913
4 μM
MIC
PMID33508505 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33508505/
RECORD: Rec_0033337 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. choleraesuis CVCC503
8 μM
MIC
PMID33508505 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33508505/
RECORD: Rec_0036979 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
<10% hemolysis at concentration tested
Hemolysis
PMID33508505 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33508505/
RECORD: Rec_0040193 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli UB 1005
4 μM
MIC
PMID33508505 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33508505/
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