Peptide Database

Peptide NameLeptin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC714H1178N192O221S4

DescriptionStandard

        VPIQKVQSDTKTLIKTIVTRINDISHTQSVSSKQRVTGLDFIPGLHPVLTLSQMDQTLAIYQQILINLPSRNVIQISNDLENLRDLLHLLAFSKSCHLPLASGLETLESLGDVLEASLYSTEVVALSRLQGSLQDMLWQLDLSPGC
    

Molecular Weight16116.40 Da

Isoelectric Point (pI)5.42

Net Charge (pH 7.0)-3.92

Net Charge (pH 7.4) -4.39

Charge Density (pH 7.0) -0.0268

GRAVY Index0.12

Hydrophobic Moment 0.66

Boman Index0.11

Instability Index45.30

Aliphatic Index 124.79

Aromaticity 0.0342

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6641.59

LogP -66.94

H-bond Donors 228.0

H-bond Acceptors 225.0

Rotatable Bonds 543.0

Heavy Atoms 1131.0

Ring Count 16.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0214183 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyLeptin

Tax ID9544

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic