Peptide Database

Peptide NameBeta-defensin 3 (BNBD-3) (BNDB-3)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC277H451N89O69S6

DescriptionStandard

        LALLFLVLSAGSGFTQGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW
    

Molecular Weight6324.49 Da

Isoelectric Point (pI)11.20

Net Charge (pH 7.0)8.79

Net Charge (pH 7.4) 8.44

Charge Density (pH 7.0) 0.1542

GRAVY Index0.22

Hydrophobic Moment 0.76

Boman Index0.02

Instability Index19.91

Aliphatic Index 85.44

Aromaticity 0.0877

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2546.21

LogP -27.18

H-bond Donors 99.0

H-bond Acceptors 85.0

Rotatable Bonds 203.0

Heavy Atoms 441.0

Ring Count 10.0

Amide Bonds 60.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0360042 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0411691 VERIFIED: YES