Peptide Database

Peptide NameCircularin A uberolysin family circular bacteriocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC456H759N119O127S2

DescriptionStandard

        MKIKKVLSGTLGLGVVGSVLALNQFSGGGLADLTIKYEIDAARAYQVVNALEWASDMSAVIGFVGGILGAGIGGAALTAAIAIAKRKLLKEGKKAAVLY
    

Molecular Weight10004.75 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)4.50

Net Charge (pH 7.4) 4.26

Charge Density (pH 7.0) 0.0455

GRAVY Index0.68

Hydrophobic Moment 0.77

Boman Index0.30

Instability Index7.56

Aliphatic Index 126.26

Aromaticity 0.0606

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3907.58

LogP -32.76

H-bond Donors 137.0

H-bond Acceptors 134.0

Rotatable Bonds 343.0

Heavy Atoms 704.0

Ring Count 7.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0325395 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus cereus [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal