Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC751H1172N218O221S7

DescriptionStandard

        MGSKVQFNPRSRTDAIFVHCSATKPEMDIGVETIRMWHKQQGWLDVGYHFIIKRDGTVEEGRPVNVVGSHVKDWNSRSVGVCLVGGIDANGKFEANFTPAQMNSLRNKLSDLKVLYPQAEIKAHHDVAPKACPSFDLQRWLSTNELITSDHG
    

Molecular Weight17015.12 Da

Isoelectric Point (pI)7.79

Net Charge (pH 7.0)1.10

Net Charge (pH 7.4) 0.45

Charge Density (pH 7.0) 0.0072

GRAVY Index-0.43

Hydrophobic Moment 0.57

Boman Index-0.02

Instability Index45.38

Aliphatic Index 76.25

Aromaticity 0.0789

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7057.17

LogP -72.94

H-bond Donors 245.0

H-bond Acceptors 236.0

Rotatable Bonds 562.0

Heavy Atoms 1197.0

Ring Count 30.0

Amide Bonds 165.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0172944 VERIFIED: YES

Provenance & Taxonomy

OrganismCitrobacter phage CR44b [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic