Peptide Database

Peptide NameNeuropeptide B-23

Function Ontology

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC113H174N34O31

DescriptionStandard

        WYKPAAGHSSYSVGRAAGLLSGLR
    

Molecular Weight2504.80 Da

Isoelectric Point (pI)10.28

Net Charge (pH 7.0)2.84

Net Charge (pH 7.4) 2.59

Charge Density (pH 7.0) 0.1185

GRAVY Index-0.13

Hydrophobic Moment 0.39

Boman Index0.10

Instability Index26.98

Aliphatic Index 77.50

Aromaticity 0.1250

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1039.50

LogP -11.33

H-bond Donors 39.0

H-bond Acceptors 35.0

Rotatable Bonds 77.0

Heavy Atoms 178.0

Ring Count 6.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0126268 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyNeuropeptide B/W

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

RECORD: Rec_0156953 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication

RECORD: Rec_0371793 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyNeuropeptide

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Analgesic Pronociceptive Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Receptor modulation Feeding regulator

Half-LifeMammalian: 2.8 hour; Yeast: 3 min; E. coli: 2 min