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MYP_031111
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Basic Information
K18 (Derived from ATG16)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C122H203N49O30
Standard
Sequence
RWKRHISEQLRRRDRLQRQAF
Physicochemical Analysis
2836.23 Da
12.00
5.85
5.59
0.2786
-1.96
0.79
-0.85
185.59
60.48
0.0952
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1373.21
-13.71
52.0
37.0
100.0
201.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0276756 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
120 μM
MIC
PMID31145591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31145591/
RECORD: Rec_0362116 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
60-120 μM
MIC
PMID31145591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31145591/
RECORD: Rec_0376311 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
60-120 μM
MIC
PMID31145591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31145591/
RECORD: Rec_0394684 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
mouse blood cells
PMID31145591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31145591/
RECORD: Rec_0420502 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
28.8-57.6 μM
MIC
PMID31145591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31145591/
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