Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length163 amino acids

Chemical FormulaC841H1300N216O236S17

DescriptionStandard

        MPFCSLHIILQTLESSLTLKTLYCFSILGLRICWSFPEILFAFCIPCCLLSSFLPCHGLSITGWFVERCWKNNIGHCRKRCFHIERYKLLCMNKLSCCIPLTSDDPYTQWPIHPTLLEDVTAEFITRDDIPFTPVSGMDDSFTIEMTQESTAIRARSSQRDSS
    

Molecular Weight18757.73 Da

Isoelectric Point (pI)6.18

Net Charge (pH 7.0)-2.17

Net Charge (pH 7.4) -2.86

Charge Density (pH 7.0) -0.0133

GRAVY Index0.16

Hydrophobic Moment 0.52

Boman Index0.12

Instability Index64.78

Aliphatic Index 89.14

Aromaticity 0.1104

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 27220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7149.40

LogP -62.37

H-bond Donors 264.0

H-bond Acceptors 256.0

Rotatable Bonds 601.0

Heavy Atoms 1310.0

Ring Count 37.0

Amide Bonds 169.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0016687 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus [Animal]

FamilyDefensin

Tax ID72004

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal